Cylindrocyclin A, a New Cytotoxic Cyclopeptide from Cylindrocarpon sp.
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چکیده
منابع مشابه
Antioxidant and cytotoxic activities of metabolites produced by a new marine Streptomyces sp. isolated from the sea cucumber Holothuria leucospilota
Marine microorganisms are important sources for novel natural products. Hence, the aim of this study was introducing the marine microorganisms with capability to produce antioxidant and cytotoxic metabolites. For this purpose, ten live sea cucumbers (Holothuria leucospilota) were collected from Larak Island. Then, their intestine contents were serially diluted and treated by heating (55 °c). 10...
متن کاملAntioxidant and cytotoxic activities of metabolites produced by a new marine Streptomyces sp. isolated from the sea cucumber Holothuria leucospilota
Marine microorganisms are important sources for novel natural products. Hence, the aim of this study was to introduce marine microorganisms with the capability of producing antioxidant and cytotoxic metabolites. For this purpose, ten live sea cucumbers (Holothuria leucospilota) were collected from Larak Island, Persian Gulf. Then, their intestine contents were serially diluted and treated by he...
متن کاملCytotoxic Sesterterpenoids from a Sponge Hippospongia sp.
One new pentacyclic sesterterpene, hippospongide A (1), and one new scalarane sesterterpenoid, hippospongide B (2), along with six previously reported known scalarane-type sesterterpenes (3-8), were isolated from a sponge Hippospongia sp. The structures of these compounds were elucidated on the basis of their spectroscopic data and comparison of the NMR data with those of known analogues. These...
متن کاملAJI9561, a new cytotoxic benzoxazole derivative produced by Streptomyces sp.
(Traders) 1.0%, yeast extract 0.1%, and CaCO3 0.2% (pH 7.2). The fermentation was carried out at 28°C on a rotary shaker (180 rpm) for 96 hours. The culture broth of Streptomyces sp. AJ9561 (5 liters) was filtered to obtain mycelium, which was extracted with acetone (3 liters) at room temperature. The extract was concentrated in vacuo to an aqueous suspension, which was extracted with EtOAc (50...
متن کاملNew cytotoxic cyclic peroxide acids from Plakortis sp. marine sponge.
Bioassay-guided fractionation of the extract of Jamaican marine sponge Plakortis sp. followed by preparative TLC and HPLC yielded several known methyl ester cyclic peroxides (1a, 2a, 3a, 4, 5), known plakortides (6,7), known bicyclic lactone (8) and new cyclic peroxide acids (1b, 2b, 3b). The chemical structures were elucidated by extensive interpretation of their spectroscopic data. These natu...
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ژورنال
عنوان ژورنال: The Journal of Antibiotics
سال: 2006
ISSN: 0021-8820,1881-1469
DOI: 10.1038/ja.2006.69